الأحد، 15 مارس 2015

Pictures of The Body Building Dog ----Myostatin Mutation ("Bully" Whippet) Double Muscling

Ever seen a dog who has biceps and looks like he goes to gym everyday.Check out these pics:

See More -- Scientific Breaktrough :Lab develops artificial human penis




Credits -Radio One Lebanon on Facebook

But this is not due to gym it is Myostatin Mutation ("Bully" Whippet)/ Double Muscling

Animals lacking myostatin or animals treated with substances that block the activity of myostatin have significantly larger muscles. This could be of economic benefit to the livestock industry. However these animals require special care and feeding which offsets the potential economic advantage.

Mutations in both copies of the human myostatin gene results in individuals that have significantly more muscle mass and hence are considerably stronger than normal. However, because this added muscle mass is not necessarily the product of exercise-mediated growth, it may not form with the same level of useful and purposeful tone and structure as normal muscle growth, as is seen in the relationship between cardiac muscle growth and cardiomyopathy. Furthermore, blocking the activity of myostatin may have therapeutic application in treating muscle wasting diseases such as muscular dystrophy.



A 2007 NIH study in PLOS Genetics[14] found a significant relationship in whippets between a myostatin mutation and racing performance. Whippets that were heterozygous for a 2 base pair deletion in the myostatin gene were significantly over-represented in the top racing classes. The mutation resulted in a truncated myostatin protein, likely resulting in an inactive form of myostatin.

Whippets with a homozygous deletion were apparently less able runners although their overall appearance was significantly more muscular. Whippets with the homozygous deletion also had an unusual body shape, with a broader head, pronounced overbite, shorter legs, and thicker tails. These whippets have also been called "bully whippets" by the breeding community due to their size. Despite the name "bully", these dogs tend to have a friendly and positive demeanour towards people as usual for whippets.

This particular mutation was not found in other muscular dog breeds such as boxers and mastiffs, nor was it found in other sighthounds such as greyhounds, Italian greyhounds, or Afghan hounds. The authors of the study suggest that myostatin mutation may not be desirable in greyhounds, the whippets' nearest relative, because greyhound racing requires more significant endurance due to the longer races (900 meters for greyhounds vs. 300 meters for whippets). 

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